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WebJul 14, 2024 · Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic disease, with an estimated incidence at birth of 1/6.000 to 1/10.000. 1–3 It represents a multisystem condition, defined by the development of benign, noninvasive tumors called hamartomas in several organ systems, most commonly in the brain, kidney, heart and skin. WebAug 16, 2024 · 1 INTRODUCTION. Tuberous sclerosis complex (TSC) is a multisystem genetic disorder associated with a wide range of physical manifestations, including in the brain, skin, kidney, eye, and lung (Curatolo, Moavero, & de Vries, 2015; Henske, Jozwiak, Kingswood, Sampson, & Thiele, 2016).These manifestations have an age-related … eric dowling lenox ma
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