The brain-testicular axis
The HPG axis plays a critical part in the development and regulation of a number of the body's systems, such as the reproductive and immune systems. Fluctuations in this axis cause changes in the hormones produced by each gland and have various local and systemic effects on the body. See more The hypothalamic–pituitary–gonadal axis (HPG axis, also known as the hypothalamic–pituitary–ovarian/testicular axis) refers to the hypothalamus, pituitary gland, and gonadal glands as if these individual See more The hypothalamus is located in the brain and secretes GnRH. GnRH travels down the anterior portion of the pituitary via the hypophyseal portal system and binds to receptors on the secretory cells of the adenohypophysis. In response to GnRH stimulation these … See more Environment can have large impact on the HPG axis. For example, women with eating disorders tend to have oligomenorrhea and secondary … See more • Biology portal • Medicine portal • Hypothalamic–pituitary–adrenal axis • Hypothalamic–pituitary–thyroid axis See more Reproduction One of the most important functions of the HPG axis is to regulate reproduction by controlling the uterine and ovarian cycles. In females, the See more Disorders Disorders of the hypothalamic–pituitary–gonadal axis are classified by the … See more The HPG axis is highly conserved in the animal kingdom. While reproductive patterns may vary, the physical components and control mechanisms remain the same. The same hormones are used with some minor evolutionary modifications. Much … See more WebThe hypothalamic-pituitary-gonadal axis (HPG axis) is the overarching system responsible for the regulation of sex steroid hormones. The Organizational-Activational Hypothesis is …
The brain-testicular axis
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WebNov 10, 2024 · During embryonic development in mammals, the testicles generally descend into the scrotum, making the testicular temperature 2–4 °C lower than the core temperature via heat exchange and clearance, and thus more beneficial for normal spermatogenesis. Failure to descend, known as cryptorchidism, carries a series of risks such as infertility … WebThe onset of puberty is signaled by high pulses of GnRH secreted by the hypothalamus; this in turn signals the release of FSH and LH from the pituitary gland. FSH causes the Sertoli cells of the testes (which help nurse developing sperm cells) to begin the process of spermatogenesis in the testes.
WebJul 26, 2024 · The axis is composed of the hypothalamic gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), and the gonadal steroids. GnRH is the central regulator of the male reproductive hormonal cascade. WebThe hypothalamic-pituitary-adrenal (HPA) axis is the major endocrine stress axis of the human organism. Cortisol, the final hormone of this axis, affects metabolic, …
WebTesticular apoptotic cells were stained, and the number of positive cells was used to detect the toxic effect of inhaled anaesthetics on the reproductive system. ... In addition, during the critical period of male brain differentiation, ... such as apoptosis and oxidation, and did not further study the regulatory role of the HPA axis, which ... WebJun 2, 2024 · Since brain plays a key role in the control of testis function, particularly by the secretion of gonadotropin-releasing hormone (GnRH), luteinizing hormone (LH) and follicle-stimulating hormone (FSH) by the hypothalamus and pituitary, we expected more common specific proteins involved in testis function/development.
WebAlthough the androgen receptor (AR) has been implicated in the promotion of apoptosis in testicular cells (TSCs), the molecular pathway underlying AR-mediated apoptosis and its sensitivity to environmental hormones in TSCs and induced pluripotent stem cells (iPSCs) remain unclear. We generated the iPSCs from bovine TSCs via the electroporation of …
WebCollectively, co-exposure to As and Mn suppressed the brain-pituitary-testicular axis function and the post-testicular events such as sperm function possibly via a mechanism involving persistent oxidative stress and endocrine disruption in the exposed rats. Keywords: Arsenic; Co-exposure; Manganese ... hallelujah lyrics lisaWebThe Hypothalamic-Pituitary-Testicular Axis is a complex system, and therefore can be damaged by many pathological effects on the many pieces if the system. Liver and … hallelujah lyrics eurovision 1979Web43) The brain-testicular axis _____. A) is the tight relationship between the cortex and the control of testicular function B) involves FSH and LH release C) involves posterior pituitary release of regulating hormones D) involves a positive feedback loop control of spermatogenesis Answer hallelujah lyrics italianoWebIt is a part of the brain, extending down from the hypothalamus, and contains mostly nerve fibers and neuroglial cells, which support axons that extend from the hypothalamus to the posterior pituitary. The posterior pituitary and the infundibulum together are referred to as the neurohypophysis. pittsealWeb61974. Anatomical terms of neuroanatomy. [ edit on Wikidata] The stria terminalis (or terminal stria) is a structure in the brain consisting of a band of fibers running along the … pittsburg ks jimmy johnsWebConclusion. Monosodium glutamate can cause GnRH damage, neuroendocrine disorders, decreased FSH, LH, and T levels, testicular spermatogenesis damage, and increased apoptotic cells, which do not improve naturally with time. MSG is a main flavor enhancer, which is widely used in food processing and cooking. pitts glassesWebMar 21, 2024 · Background: Survivors of testicular germ cell tumors (GCT) may suffer from late cognitive impairment. We hypothesized that disruption of intestinal barrier during chemotherapy and/or radiotherapy may be a contributing factor of cognitive dysfunction within the gut-blood-brain axis. pittsburg oil