Circherc4
WebNational Center for Biotechnology Information WebImmunostaining of Ki67 expression in xenografts tumor tissues after intratumoral circHERC4 inhibition. Browse. Search. Explore more content. 13045_2024_1210_MOESM9_ESM. pdf (5.59 MB)
Circherc4
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WebColorectal cancer (CRC) is one of the most commonly diagnosed cancers and a leading cause of cancer-related deaths worldwide according to the latest global cancer statistics [ 1 ]. Until now, surgical resection is still the primary radical … WebSun Yat-sen University: circHERC4 promotes colorectal cancer metastasis. Journal of Hematology and Oncology——[17.388] ① Two pairs of colorectal cancer (CRC) and normal tissues adjacent to the cancer were subjected to circRNA-seq analysis of the up-regulated circRNA, and cell invasion experiments were used to verify the function; ② circHERC4 …
WebCircular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer. #CRC … WebGalectin Therapeutics c ihc staining C Ihc Staining, supplied by Galectin Therapeutics, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations.
WebCircular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer Jiehua He, Ziqiang Chu, WebSilencing of circHERC4 significantly inhibited the proliferation and migration of two highly aggressive CRC cell lines and reduced liver and lung metastasis in vivo. Mechanistically, we revealed that circHERC4 inactivated the tumor suppressor, miR-556-5p, leading to the activation of CTBP2/E-cadherin pathway which promotes tumor metastasis in CRC.
WebSep 14, 2024 · Some circRNAs negatively regulate miRNA-mediated gene silencing by acting as competitive endogenous RNAs (ceRNAs) (Fig. 2A). circHERC4 was recently found to exhibit oncogenic effects in CRC, by ...
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